Cell biology, microscopy, and image analysis.
We study how cells move, interact with their surroundings, and cross tissue barriers. We combine cell biology with microscopy and quantitative image analysis, and we develop tools that make complex imaging experiments easier to analyse and share.
Featured research: biology
CCT8 associates with the MYO10 motor domain and regulates filopodia and breast cancer cell invasion
Pancreatic cancer cells breach endothelial barriers through protrusion-driven invasion or endothelial retraction
Filopodia-mediated trans-endocytosis
Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers
Time, the final frontier
TLNRD1 is a CCM complex component and regulates endothelial barrier integrity
Myosin-X recruits lamellipodin to filopodia tips
MYO10-filopodia support basement membranes at pre-invasive tumor boundaries
Featured research: methods and tools
Rxiv-Maker: An automated template engine for streamlined scientific publications
NucleiSky enables cross-scale multimodal registration of microscopy data using nuclei constellations
Customizable FDM-based zebrafish larvae mold for live imaging
Packaging Jupyter notebooks as installable desktop apps using LabConstrictor
EZInput: A Cross-Environment Python Library for Easy UI Generation in Scientific Computing
Practical considerations for data exploration in quantitative cell biology
CellTracksColab is a platform that enables compilation, analysis, and exploration of cell tracking data
DL4MicEverywhere: deep learning for microscopy made flexible, shareable and reproducible
All featured research (32) · All publications
